A Simple Key For pentobarbital of sodium Unveiled
A Simple Key For pentobarbital of sodium Unveiled
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pentobarbital will lower the extent or effect of naloxegol by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Usage of naloxegol with solid CYP3A4 inducers just isn't advisable
pentobarbital will lower the extent or effect of mavacamten by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated.
Watch Intently (one)pentobarbital will reduce the level or effect of mifepristone by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Monitor. CYP3A4 inducers haven't been analyzed, coadministration not suggested by company
pentobarbital will reduce the extent or effect of diltiazem by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Monitor.
Phenytoin, sodium valproate, valproic acid: The effect of barbiturates around the metabolism of phenytoin seems to become variable. Some investigators report an accelerating effect, even though others report no effect. Because the effect of barbiturates within the metabolism of phenytoin is not really predictable, phenytoin and barbiturate blood amounts really should be monitored a lot more often if these drugs are supplied concurrently.
pentobarbital will reduce the extent or effect of meloxicam by influencing hepatic enzyme CYP2C9/ten metabolism. Minor/Importance Unknown.
pentobarbital will reduce the level or effect click here of tamoxifen by impacting hepatic enzyme CYP2C9/10 metabolism. Use Caution/Watch.
pentobarbital will lessen the extent or effect of pimozide by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Minimal/Significance Unknown.
pentobarbital will decrease the extent or effect of disopyramide by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Minor/Importance Unidentified.
Corticosteroids: Barbiturates seem to improve the metabolism of exogenous corticosteroids possibly through the induction of hepatic microsomal enzymes. Clients stabilized on corticosteroid therapy might have to have dosage changes if barbiturates are added to or withdrawn from their dosage regimen.
Griseofulvin: Phenobarbital seems to interfere with the absorption of orally administered griseofulvin, thus decreasing its blood level.
pentobarbital will minimize the level or effect of quinidine by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor.
pentobarbital will reduce the extent or effect of dexamethasone by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Watch.
pentobarbital will lower the level or effect of vardenafil by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Observe.